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Your DNA Doesn’t Change.
How Your Genes Express Themselves, Does. Every Day.
Prajeeva offers three complementary tests that together provide a layered genetic and epigenetic picture: biological age tracking through TruDiagnostic’s TrueAge™, epigenetic health assessment through TrueHealth™, and functional genomic profiling through TheDNACompany’s 360 DNA™. Each is physician-interpreted. None is used in isolation.
The Three Tests Prajeeva Offers
Each test reads a different layer of your biology. Together, they tell the physician what you inherited, how you are ageing at a cellular level, and how your genes are currently functioning in relation to your environment, lifestyle and health choices.
Genetic tests reveal biological predispositions, not diagnostic certainties. A variant does not constitute a diagnosis. At Prajeeva, every genetic and epigenetic result is interpreted by a physician in the context of your clinical history, presenting symptoms, and conventional biomarker data. No clinical action is taken on a genetic finding in isolation.
Speak With Our Medical Team About Genetic TestingBiological Age - The Number That Matters More Than Your Birthdate
Your chronological age is fixed. Your biological age — the age at which your cells, organs, and tissues are functioning — is not. It can be younger or older than your years on earth, and the gap between the two is one of the most clinically informative outputs available in preventive medicine today.
TrueAge™ by TruDiagnostic measures biological age using DNA methylation — chemical modifications to the genome that change in reproducible patterns with ageing and in response to lifestyle, environment, and health interventions. The DunedinPACE™ algorithm, derived from a longitudinal cohort study in Dunedin, New Zealand, that has tracked over a thousand individuals for five decades, addresses a specific clinical question: for every calendar year that passes, how many biological years is this person’s body ageing? A value below 1.0 indicates ageing at a slower rate than average; above 1.0 indicates a faster rate.
SYMPHONYAge™, developed at Yale University, extends this to provide individual biological age estimates for 11 organ systems — brain, heart, liver, kidney, lung, immune, metabolic, hormonal, musculoskeletal, inflammatory, and metabolic sub-systems. Two individuals with the same overall biological age may have very different organ-system profiles, and the clinical priorities for each differ accordingly.
Epigenetic age testing is increasingly used in longevity medicine to objectively monitor biological responses to lifestyle and therapeutic interventions. Serial testing at defined intervals allows physicians and patients to assess whether protocols are producing measurable change at the cellular level.
Explore the Live Longer Programme
Functional Genomics - How Your Genes Interact With Your Environment
The 360 DNA™ test by TheDNACompany analyses genetic variants — single nucleotide polymorphisms (SNPs) — across biological pathways that govern how the body processes nutrients, metabolises hormones, clears environmental toxins, regulates inflammatory responses, and produces neurotransmitters.
Variants in genes such as MTHFR, COMT, CYP450, GST, APOE, and others may influence nutrient metabolism, detoxification pathways, inflammatory responses, and susceptibility to certain health conditions. These findings require interpretation alongside clinical assessment and conventional laboratory investigations.
Pathway
Clinical Relevance At Prajeeva
Methylation
Gene variants in this pathway may influence folate and B-vitamin utilisation, homocysteine metabolism, and DNA repair capacity. Informs personalised nutritional supplementation and cardiovascular risk assessment.
Detoxification (Phase I & Ii)
Variants affecting liver enzyme activity (CYP450, GST, NQO1 pathways) may influence medication metabolism, hormone clearance, and the body’s capacity to process environmental chemical exposures.
Hormonal Pathways
Variants in oestrogen metabolism, testosterone sensitivity, and cortisol response genes may provide context for hormonal health assessments and HPA axis management.
Cardiovascular
Variants including APOE status may inform lipid management strategy, omega-3 dosing, and the intensity of cardiovascular monitoring in the longevity programme.
Inflammatory Response
Genetic predisposition patterns affecting inflammatory signalling may inform the frequency of inflammatory biomarker monitoring and anti-inflammatory protocol design.
Neurotransmitter Synthesis
Variants in dopamine, serotonin, and norepinephrine pathways may provide supporting context for cognitive performance, mood, and stress resilience assessments.
The 360 DNA™ report is a probabilistic clinical guide, not a predictive diagnostic. Every finding is interpreted by the Prajeeva physician alongside your biomarker panel, clinical history, and current health status before informing any protocol recommendation.
Discuss Your Genomic Profile With Our Medical Team
How Genetic Testing
Works at Prajeeva
Clinical Note : Genetic and epigenetic tests are adjunctive tools that support personalised risk assessment and precision medicine. They do not independently diagnose disease and should always be interpreted in conjunction with clinical history, physical examination, conventional laboratory biomarkers, and physician judgement. Results are intended to inform clinical decision-making, not to replace it.
